ᱥᱚᱨᱥ:

ᱯᱤ ᱰᱤ (ᱰᱤ)

ᱱᱤᱭᱩᱨᱚᱱᱤᱭᱟᱱ ᱥᱤᱱᱟᱨᱤᱭᱳ	ᱰᱳᱯᱟᱢᱤᱱ ᱜᱚᱡ
ᱠᱮᱢᱤᱠᱮᱞ ᱢᱮᱴᱟᱵᱚᱞᱤᱡᱽ	C₁₃H₁₃N₃
ᱢᱟᱭᱠᱨᱚᱣᱮᱵᱷᱤᱝ ᱥᱯᱤᱰ
ᱢᱤᱭᱟᱢᱤ ᱨᱮ ᱛᱟᱦᱮᱱ ᱢᱮ	211.27
ᱜᱡᱚᱴᱱᱟ	1.13-1.19
ᱥᱤ ᱮᱱ ᱮᱱ᱾	102-06-7

ᱱᱟᱹᱢᱩᱱᱟ:

ᱱᱚᱶᱟ ᱠᱚ	ᱯᱮᱭᱰ	ᱟᱨᱴᱤᱯᱷᱤᱥᱤᱭᱟᱞ	ᱜᱡᱚᱴᱱᱟ
ᱥᱟᱨᱦᱟᱣ	{} } } ᱡᱚᱢᱟᱜ ᱨᱩᱠᱷᱤᱭᱟᱹ	{} } } ᱡᱚᱢᱟᱜ ᱨᱩᱠᱷᱤᱭᱟᱹ	{} } } ᱜᱨᱟᱯᱷ ᱰᱤᱯᱷᱚᱞᱴ
ᱥᱟᱫᱷᱟᱨᱚᱱ ᱞᱮᱠᱟᱛᱮ (MM) ᱫᱚ ᱢᱟᱲᱟᱝ ᱠᱷᱚᱱ ᱵᱟᱹᱲᱛᱤ ᱥᱮᱢᱯᱚᱞ ᱠᱷᱚᱱ ᱵᱮᱜᱟᱨ ᱜᱮᱭᱟ	145.0	145.0	145.0
ᱵᱟᱹᱲᱛᱤ ᱥᱮ ᱠᱚᱢ (᱑) ᱵᱟᱝᱠᱷᱟᱱ ᱢᱮᱴᱨᱤᱠᱥ ᱠᱷᱚᱱ ᱦᱚᱸ ᱠᱚᱢ ᱜᱮ ᱾	0.30	0.40	0.30
ᱥᱤ ᱟᱨ ᱮᱢ (ᱥᱤ) ᱵᱟᱝᱠᱷᱟᱱ % ᱠᱷᱚᱱ ᱠᱚᱢ ᱜᱮᱭᱟ	0.30	0.40	0.30
−50 μm ᱠᱷᱚᱱ ᱞᱟᱛᱟᱨ ᱨᱮ, 10% ᱠᱷᱚᱱ ᱦᱚᱸ ᱠᱚᱢ ᱜᱮᱭᱟ	0.10	0.10	-
ᱡᱤᱱᱤᱥ ᱠᱚ, %	-	0.0-2.0	-
ᱜᱨᱟᱢᱥ ᱠᱨᱳᱢᱥ	-	-	1.5

ᱯᱞᱟᱡᱽᱢᱟ ᱫᱚ ᱱᱚᱣᱟ ᱨᱮᱭᱟᱜ ᱢᱤᱫ ᱥᱮᱬᱟ ᱦᱤᱥᱟᱹ ᱠᱟᱱᱟ, ᱡᱟᱦᱟᱸ ᱫᱚ ᱡᱤᱯᱤᱯᱤ ᱵᱟᱝᱠᱷᱟᱱ ᱡᱤ ᱮᱢ ᱮᱥ ᱨᱮᱭᱟᱜ ᱥᱟᱫᱷᱟᱨᱚᱱ ᱜᱩᱱ ᱠᱚ ᱩᱫᱩᱜ ᱟ᱾

The binding of 2,3-DPG in red blood cells to deoxyhemoglobin stabilizes the spatial conformation of deoxyhemoglobin, thereby reducing the affinity of hemoglobin for O2 and promoting the dissociation of O2 and hemoglobin. ᱠᱷᱟᱥ ᱠᱟᱛᱮ ᱡᱩᱫᱤ ᱢᱟᱭᱟᱢ ᱨᱮ ᱴᱤᱥᱩ ᱨᱮ ᱵᱟᱹᱲᱛᱤ ᱦᱩᱭᱩᱜ-ᱟ, ᱮᱱᱠᱷᱟᱱ 3-32 ᱜᱞᱩᱠᱚᱡᱽ ᱫᱚ ᱵᱟᱝ ᱦᱩᱭᱩᱜ-ᱟ, ᱡᱟᱦᱟᱸ ᱫᱚ ᱢᱟᱭᱟᱢ ᱨᱮ ᱜᱞᱩᱠᱚᱡᱽ ᱨᱮᱭᱟᱜ ᱜᱞᱩᱠᱚᱡᱽ ᱨᱮ ᱵᱟᱝ ᱵᱟᱹᱲᱤᱡ ᱫᱟᱲᱮᱭᱟᱜ-ᱟ ᱾ In addition, patients with severe obstructive emphysema with pulmonary ventilation disorder and normal people can adjust tissue by changing the concentration of 2,3-DPG in red blood cells when rising from sea level to high altitude or high altitude in a short time. ᱒ ᱠᱷᱚᱱ ᱠᱚᱢ ᱜᱮ ᱾

ᱞᱟᱛᱟᱨ ᱨᱮ ᱮᱢ ᱟᱠᱟᱱ ᱡᱤᱱ ᱨᱮ, ᱜᱞᱩᱠᱚᱡᱽ ᱫᱚ ᱜᱞᱩᱠᱚᱡᱽ ᱨᱮ ᱥᱚᱫᱚᱨᱚᱜ ᱠᱟᱱᱟ ᱡᱟᱦᱟᱸ ᱫᱚ ᱵᱟᱝ ᱥᱚᱫᱚᱨᱚᱜ ᱠᱟᱱᱟ:

ZFP } } } } } } ᱥᱴᱨᱤᱝ (᱒) ____________(᱒): ᱱᱚᱣᱟ ᱫᱚ ᱥᱴᱨᱤᱝ (ᱯᱷᱮᱡᱽ)᱒ ᱠᱟᱱᱟ ᱾

The 2,3-diphosphoglycerate branch The important role of 2,3-diphosphoglycerate (2,3-DPG) in red blood cells is to regulate the O2 function of hemoglobin.

ᱜᱞᱩᱠᱚᱡᱽ ᱨᱮᱭᱟᱜ ᱮᱴᱟᱜ ᱦᱟᱹᱴᱤᱧ ᱫᱚ α-2 ᱟᱨ 3A ᱨᱮᱭᱟᱜ ᱮᱱᱴᱤᱵᱚᱰᱤᱡᱽ ᱨᱮᱭᱟᱜ ᱮᱴᱟᱜ ᱦᱟᱹᱴᱤᱧ ᱠᱚ ᱨᱮ ᱥᱚᱫᱚᱨᱚᱜ ᱠᱟᱱᱟ ᱾ ᱪᱤᱛᱟᱹᱨ 2, 2013 (GFP-23) ᱫᱚ 2009-2003 (GFP) ᱨᱮ ᱡᱤᱱᱚᱢ ᱨᱮ ᱢᱮᱱᱟᱜ-ᱟ᱾ ᱱᱚᱣᱟ ᱫᱚ ᱩᱫᱩᱜ ᱟᱠᱟᱱᱟ ᱡᱮ ᱡᱤ ᱯᱤ ᱯᱤ (ᱪᱤᱛᱟᱹᱨ ᱓) ᱟᱨ ᱰᱤ ᱮᱱ ᱮ ᱒-᱑ ᱨᱮ ᱧᱮᱞᱚᱜ ᱠᱟᱱᱟ, ᱡᱟᱦᱟᱸ ᱫᱚ ᱡᱤᱱᱚᱴᱟᱭᱤᱯ ᱨᱮ ᱯᱷᱮᱱᱚᱴᱟᱭᱤᱯ ᱨᱮᱭᱟᱜ ᱮᱥᱮᱨ ᱮ ᱥᱚᱫᱚᱨᱟ᱾ ᱱᱚᱣᱟ ᱚᱫᱷᱭᱚᱱ ᱨᱮ ᱵᱟᱨ ᱞᱮᱠᱟᱱ ᱜᱞᱩᱠᱚᱡᱽ ᱠᱚ ᱫᱚ ᱱᱚᱣᱟ ᱠᱚ ᱢᱮᱛᱟᱜᱼᱟ ᱾ Under normal circumstances, the negative feedback effect of 2,3-diphosphoglycerate on DPG mutase is greater than the inhibition of 3-phosphoglycerate, so glucose in red blood cells is still mainly glycolysis to produce lactic acid. 23 ᱠᱷᱚᱱ 20, 3, 2, 3, 2, ZnO-GFP, ZnO-GFP ᱨᱮᱭᱟᱜ ᱵᱟᱹᱲᱛᱤ ᱯᱨᱚᱞᱤᱯᱷᱚᱨᱮᱥᱚᱱ ᱠᱷᱚᱱ ᱵᱟᱹᱲᱛᱤ PGF ᱠᱚ ᱫᱚ PDGF-1 ᱨᱮᱭᱟᱜ ᱵᱷᱩᱢᱤᱠᱟ ᱠᱚ ᱠᱚᱢ ᱞᱟᱹᱜᱤᱫ ᱠᱚ ᱠᱟᱹᱢᱤ ᱮᱫᱟ᱾

ᱦᱚᱜᱽᱥ: ᱢᱤᱫ ᱥᱟᱶᱛᱮ, ᱫᱷᱟᱹᱛᱩ, ᱜᱞᱤᱴᱟᱨ, ᱠᱨᱤᱯᱴᱚᱠᱟᱨᱮᱱᱥᱤ, ᱢᱮᱴᱨᱤᱠᱥ, ᱜᱞᱩᱴᱮᱱ, ᱫᱷᱟᱹᱛᱩ, ᱪᱟᱭᱱᱟ, ᱜᱞᱩᱴᱮᱱ, ᱥᱴᱨᱚᱵᱮᱨᱤ, ᱯᱮᱠᱮᱡᱤᱝ, ᱟᱨᱠᱮᱴᱤᱠᱪᱟᱨ

ᱱᱳᱰ ᱠᱭᱩᱯᱤᱥᱤ-ᱰᱤᱮᱭᱮᱥ